Pharmaceutical & Biotech Processing Solutions
VALVA delivers ultra-high purity flow control solutions designed for the rigorous demands of the life sciences industry. In a sector where patient safety and batch integrity are non-negotiable, our valves provide the sterile performance required for everything from active pharmaceutical ingredient (API) synthesis to large-scale bioreactor systems.
Engineered for Sterile Integrity
Bioprocessing requires equipment that can be completely sterilized and leaves no residue. VALVA addresses these critical pharmaceutical challenges through:
- Crevice-Free Geometry: Internal designs that eliminate “dead legs” and entrapment areas to prevent bacterial growth.
- Ultra-Fine Surface Finish: Precision electropolishing to achieve Ra ≤ 0.38μm (15 μ-in), exceeding the most stringent ASME BPE requirements.
- Full Drainability: Engineered to ensure every drop of process fluid or cleaning agent drains completely, facilitating rapid batch turnover.
- Advanced Diaphragm Technology: Utilizing high-performance PTFE and medical-grade Silicone diaphragms for absolute isolation between the process and the atmosphere.
Solutions for Life Science Applications
We support critical processes across the pharmaceutical and biotechnology spectrum:
- Bioreactors & Fermentation: Sterile sampling and harvest valves designed for sensitive cell culture environments.
- API Manufacturing: High-alloy valves (Hastelloy/Stainless Steel) for handling aggressive solvents and chemical reagents.
- WFI & Pure Water Systems: Specialized valves for Water For Injection (WFI) loops and purified water distribution.
- Fill & Finish: Precision dosing and filling valves for final drug product packaging.
- CIP / SIP Systems: Valves engineered to withstand continuous cycles of high-pressure steam and caustic cleaning agents.
High-Purity Metallurgy & Materials
We use only the highest grade materials to ensure zero leaching and maximum durability:
| Component | Recommended Material | Benefit for Pharma |
| Valve Bodies | Stainless Steel 316L (Low Sulfur) | Minimizes “rouging” and ensures high-purity weldability. |
| Aggressive Chemicals | Hastelloy C22 | Superior resistance for aggressive buffer solutions and acids. |
| Soft Seals / Diaphragms | PTFE / USP Class VI EPDM | Fully traceable, non-toxic, and resistant to repeated sterilization. |
| Surface Treatment | Electropolished (EP) | Creates a mirror-like finish that is easy to clean and highly passive. |
Compliance & Certification Standards
At VALVA, we speak the language of global pharmaceutical regulations:
- Design Standards: Fully compliant with ASME BPE (Biprocessing Equipment) standards.
- Material Compliance: All seals and diaphragms are USP Class VI and FDA compliant.
- Total Traceability: Every valve includes a comprehensive documentation package (Material Test Reports 3.1, Surface Finish Certs, and Weld Logs).
- BSE/TSE Statement: Ensuring all components are free from animal-derived ingredients to prevent contamination.